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1

Exploration of larger central ring linkers in furamidine analogues: Synthesis and evaluation of their DNA binding, antiparasitic and fluorescence properties

Abdelbasset A. Farahat, Ekaterina Paliakov, Arvind Kumar, Alaa-Eldin M. Barghash, Fatma E. Goda, Hassan M. Eisa, Tanja Wenzler, Reto Brun, Yang Liu, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 663 KB

english, 2011

2

Design and analysis of molecular motifs for specific recognition of RNA

Ke Li M. Fernandez-Saiz, C.Ted Rigl, Arvind Kumar, Kaliappa G. Ragunathan, Adrian W. McConnaughie, David W. Boykin, Hans-Jörg Schneider, W.David Wilson

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 1.63 MB

english, 1997

3

Synthesis, DNA Affinity, and Antiprotozoal Activity of Fused Ring Dicationic Compounds and Their Prodrugs

Arafa, Reem K., Brun, Reto, Wenzler, Tanja, Tanious, Farial A., Wilson, W. David, Stephens, Chad E., Boykin, David W.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 222 KB

english, 2005

4

Design and analysis of RNA structure-specific agents as potential antivirals

W. David Wilson, Lynda Ratmeyer, Min Zhao, Daoyuan Ding, Adrian W. McConnaughie, Arvind Kumar, David W. Boykin

Journal:

Journal of Molecular Recognition

Year:

1996

Language:

english

File:

PDF, 998 KB

english, 1996

5

Novel Dications with Unfused Aromatic Systems: Trithiophene and Trifuran Derivatives of Furimidazoline

Petr Bilik, Farial Tanious, Arvind Kumar, W. David Wilson, David W. Boykin, Pierre Colson, Claude Houssier, Michael Facompré, Christelle Tardy, Christian Bailly

Journal:

Year:

2001

Language:

english

File:

PDF, 241 KB

english, 2001

6

Influence of compound structure on affinity, sequence selectivity, and mode of binding to DNA for unfused aromatic dications related to furamidine

Binh Nguyen, Christelle Tardy, Christian Bailly, Pierre Colson, Claude Houssier, Arvind Kumar, David W. Boykin, W. David Wilson

Journal:

Year:

2002

Language:

english

File:

PDF, 813 KB

english, 2002

7

The interaction of multiply charged intercalating heterocycles with DNA

Terri Fairley, Frank Molock, David W. Boykin, W. David Wilson

Journal:

Year:

1988

Language:

english

File:

PDF, 854 KB

english, 1988

8

Intercalation binding of 6-substituted naphthothiopheneamides to DNA: Enthalpy and entropy components

Harry P. Hopkins Jr., Yang Ming, W. David Wilson, David W. Boykin

Journal:

Year:

1991

Language:

english

File:

PDF, 758 KB

english, 1991

9

ChemInform Abstract: Diguanidino and “Reversed” Diamidino 2,5-Diarylfurans as Antimicrobial Agents.

Chad E. Stephens, Farial Tanious, Susan Kim, W. David Wilson, Wiley A. Schell, John R. Perfect, Scott G. Franzblau, David W. Boykin

Journal:

Year:

2001

File:

PDF, 31 KB

2001

10

The Activity of Diguanidino and “Reversed” Diamidino 2,5-Diarylfurans versus Trypanosoma cruzi and Leishmania donovani.

Chad E. Stephens, Reto Brun, Manar M. Salem, Karl A. Werbovetz, Farial Tanious, W. David Wilson, David W. Boykin

Journal:

Year:

2003

File:

PDF, 79 KB

2003

11

A new approach utilizing high-resolution proton NMR in structural analysis of intercalation complexes of natural DNA

S. Chandrasekaran, S. Kusuma, David W. Boykin, W. David Wilson

Journal:

Magnetic Resonance in Chemistry

Year:

1986

Language:

english

File:

PDF, 1.22 MB

english, 1986

12

1H, 13C and 17O NMR spectral study of 4,1-disubstituted naphthalenes

Subbu Perumal, Gnanasambandam Vasuki, David A. Wilson, David W. Boykin

Journal:

Magnetic Resonance in Chemistry

Year:

1992

Language:

english

File:

PDF, 565 KB

english, 1992

13

Assignment of the carbon-13 chemical shifts of quinacrine, chloroquine and related compounds in D2O solution

Billy G. Griggs, W. David Wilson, David W. Boykin

Journal:

Magnetic Resonance in Chemistry

Year:

1978

Language:

english

File:

PDF, 584 KB

english, 1978

14

Assignment of the 13C chemical shifts of ethidium bromide and analogs in D2O solution

Billy G. Griggs, Michael W. Davidson, W. David Wilson, David Withers Boykin

Journal:

Magnetic Resonance in Chemistry

Year:

1980

Language:

english

File:

PDF, 314 KB

english, 1980

15

17O NMR studies on polycyclic quinones, hydroxyquinones and related cyclic ketones: Models for anthracycline intercalators

Subramanian Chandrasekaran, W. David Wilson, David W. Boykin

Journal:

Magnetic Resonance in Chemistry

Year:

1984

Language:

english

File:

PDF, 386 KB

english, 1984

16

The effect of intercalator structure on binding strength and base-pair specificity in DNA interactions

W.David Wilson, Yueh-Hwa Wang, S. Kusuma, S. Chandrasekaran, David W. Boykin

Journal:

Biophysical Chemistry

Year:

1986

Language:

english

File:

PDF, 783 KB

english, 1986

17

Dicationic biphenyl benzimidazole derivatives as antiprotozoal agents

Mohamed A. Ismail, Reto Brun, Tanja Wenzler, Farial A. Tanious, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 326 KB

english, 2004

18

Dicationic near-linear biphenyl benzimidazole derivatives as DNA-targeted antiprotozoal agents

Mohamed A. Ismail, Adalgisa Batista-Parra, Yi Miao, W. David Wilson, Tanja Wenzler, Reto Brun, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 219 KB

english, 2005

19

3D QSAR on a library of heterocyclic diamidine derivatives with antiparasitic activity

Prashanth Athri, Tanja Wenzler, Patricia Ruiz, Reto Brun, David W. Boykin, Richard Tidwell, W. David Wilson

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 718 KB

english, 2006

20

Azaterphenyl diamidines as antileishmanial agents

Laixing Hu, Reem K. Arafa, Mohamed A. Ismail, Tanja Wenzler, Reto Brun, Manoj Munde, W. David Wilson, Sandra Nzimiro, Serene Samyesudhas, Karl A. Werbovetz, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 266 KB

english, 2008

21

Small changes in cationic substituents of diphenylfuran derivatives have major effects on the binding affinity and the binding mode with RNA helical duplexes

Min Zhao, Lynda Ratmeyer, Robert G. Peloquin, Shijie Yao, Arvind Kumar, Jaroslaw Spychala, David W. Boykin, W. David Wilson

Journal:

Bioorganic & Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 958 KB

english, 1995

22

Dicationic DNA-targeted antiprotozoal agents: Naphthalene replacement of benzimidazole

Sarah Chackal-Catoen, Yi Miao, W. David Wilson, Tanja Wenzler, Reto Brun, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 253 KB

english, 2006

23

Synthesis and antiprotozoal activity of novel bis-benzamidino imidazo[1,2-a]pyridines and 5,6,7,8-tetrahydro-imidazo[1,2-a]pyridines

Mohamed A. Ismail, Reem K. Arafa, Tanja Wenzler, Reto Brun, Farial A. Tanious, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 226 KB

english, 2008

24

Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum

Laixing Hu, Reem K. Arafa, Mohamed A. Ismail, Alpa Patel, Manoj Munde, W. David Wilson, Tanja Wenzler, Reto Brun, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 474 KB

english, 2009

25

Dicationic phenyl-2,2′-bichalcophenes and analogues as antiprotozoal agents

Mohamed A. Ismail, Serry A. El Bialy, Reto Brun, Tanja Wenzler, Rupesh Nanjunda, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 402 KB

english, 2011

26

Structure-specific recognition of quadruplex DNA by organic cations: Influence of shape, substituents and charge

Elizabeth W. White, Farial Tanious, Mohamed A. Ismail, Anthony P. Reszka, Stephen Neidle, David W. Boykin, W. David Wilson

Journal:

Biophysical Chemistry

Year:

2007

Language:

english

File:

PDF, 1.84 MB

english, 2007

27

Sequence and length dependent thermodynamic differences in heterocyclic diamidine interactions at AT base pairs in the DNA minor groove

Yang Liu, Arvind Kumar, David W. Boykin, W. David Wilson

Journal:

Biophysical Chemistry

Year:

2007

Language:

english

File:

PDF, 2.04 MB

english, 2007

28

Synthesis and antiparasitic evaluation of bis-2,5-[4-guanidinophenyl]thiophenes

Jose L. Gonzalez, Chad E. Stephens, Tanja Wenzler, Reto Brun, Farial A. Tanious, W. David Wilson, Todd Barszcz, Karl A. Werbovetz, David W. Boykin

Journal:

European Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 210 KB

english, 2007

29

Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents

Reem K. Arafa, Mohamed A. Ismail, Manoj Munde, W. David Wilson, Tanja Wenzler, Reto Brun, David W. Boykin

Journal:

European Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 569 KB

english, 2008

30

Inhibition of the HIV-1 rev–RRE complex formation by unfused aromatic cations

Ge Xiao, Arvind Kumar, Ke Li, C.Ted Rigl, Miroslav Bajic, Tina M. Davis, David W. Boykin, W.David Wilson

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 2.16 MB

english, 2001

31

Modulation of the rev-RRE interaction by aromatic heterocyclic compounds

Maria L. Zapp, Donna W. Young, Arvind Kumar, Ravinder Singh, David W. Boykin, W.David Wilson, Michael R. Green

Journal:

Bioorganic & Medicinal Chemistry

Year:

1997

Language:

english

File:

PDF, 753 KB

english, 1997

32

Synthesis, DNA binding, fluorescence measurements and antiparasitic activity of DAPI related diamidines

Abdelbasset A. Farahat, Arvind Kumar, Martial Say, Alaa El-Din M. Barghash, Fatma E. Goda, Hassan M. Eisa, Tanja Wenzler, Reto Brun, Yang Liu, Leah Mickelson, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 575 KB

english, 2010

33

Synthesis and antiprotozoal activity of 2,5-bis[amidinoaryl]thiazoles

Danuta Branowska, Abdelbasset A. Farahat, Arvind Kumar, Tanja Wenzler, Reto Brun, Yang Liu, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 555 KB

english, 2010

34

Molecular factors governing inhibition of arylimidamides against Leishmania: Conservative computational modeling to improve chemotherapies

Catharine J. Collar, Xiaohua Zhu, Karl Werbovetz, David W. Boykin, W. David Wilson

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 1.80 MB

english, 2011

35

Dicatonic 2,4-diaryl pyrimidines as DNA selective binding agents

Arvind Kumar, Min Zhao, W. David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1994

Language:

english

File:

PDF, 401 KB

english, 1994

36

The activity of diguanidino and ‘reversed’ diamidino 2,5-diarylfurans versus Trypanosoma cruzi and Leishmania donovani

Chad E. Stephens, Reto Brun, Manar M. Salem, Karl A. Werbovetz, Farial Tanious, W.David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 178 KB

english, 2003

37

Inhibition of HIV-1 Tat-TAR interaction by diphenylfuran derivatives: effects of the terminal basic side chains

Nathalie Gelus, Christian Bailly, François Hamy, Thomas Klimkait, W.David Wilson, David W. Boykin

Journal:

Bioorganic & Medicinal Chemistry

Year:

1999

Language:

english

File:

PDF, 236 KB

english, 1999

38

Mefloquine, a clinically useful quinolinemethanol antimalarial which does not significantly bind to DNA

DAVIDSON, MICHAEL W., GRIGGS, BILLY G., BOYKIN, DAVID W., WILSON, W. DAVID

Journal:

Year:

1975

File:

PDF, 353 KB

1975

39

Novel Dicationic Imidazo[1,2-a]pyridines and 5,6,7,8-Tetrahydro-imidazo[1,2-a]pyridines as Antiprotozoal Agents

Ismail, Mohamed A., Brun, Reto, Wenzler, Tanja, Tanious, Farial A., Wilson, W. David, Boykin, David W.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 110 KB

english, 2004

40

The synthesis of a potential bisintercalating ethidium bromide analog

Irene G. Lopp, W. David Wilson, David W. Boykin

Journal:

Journal of Heterocyclic Chemistry

Year:

1982

File:

PDF, 125 KB

1982

41

Synthesis of 8-substituted naphtho[2,1-b]thiophenes with cationic side chains at position 4

Srihari Kusuma, W. David Wilson, David W. Boykin

Journal:

Journal of Heterocyclic Chemistry

Year:

1985

File:

PDF, 288 KB

1985

42

Synthesis of mono-cationic and dicationic analogs of hoechst 33258

Agnieszka Czarny, W. D. Wilson, David W. Boykin

Journal:

Journal of Heterocyclic Chemistry

Year:

1996

File:

PDF, 347 KB

1996

43

Activity of “reversed” diamidines against Trypanosoma cruzi “in vitro”

C.F. Silva, Marcos Meuser Batista, Renata Alves Mota, Elen Mello de Souza, Chad E. Stephens, Phanneth Som, David Wilson Boykin, Maria de Nazaré C. Soeiro

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.13 MB

english, 2007

44

A thermodynamic and structural analysis of DNA minor-groove complex formation

Suzann Mazur, Farial A. Tanious, Daoyuan Ding, Arvind Kumar, David W. Boykin, Ian J. Simpson, Stephen Neidle, W.David Wilson

Journal:

Journal of Molecular Biology

Year:

2000

Language:

english

File:

PDF, 400 KB

english, 2000

45

Comparative thermodynamics for monomer and dimer sequence-dependent binding of a heterocyclic dication in the DNA minor groove

Lei Wang, Arvind Kumar, David W. Boykin, Christian Bailly, W.David Wilson

Journal:

Journal of Molecular Biology

Year:

2002

Language:

english

File:

PDF, 1.15 MB

english, 2002

46

Antiparasitic compounds that target DNA

W. David Wilson, Farial A. Tanious, Amanda Mathis, Denise Tevis, James Edwin Hall, David W. Boykin

Journal:

Year:

2008

Language:

english

File:

PDF, 2.33 MB

english, 2008

47

Dicationic Diarylfurans as Anti-Pneumocystis carinii Agents

Boykin, David W., Kumar, Arvind, Spychala, Jaroslaw, Zhou, Min, Lombardy, Richard J., Wilson, W. David, Dykstra, Christine C., Jones, Susan K., Hall, James E.

Journal:

Journal of Medicinal Chemistry

Year:

1995

Language:

english

File:

PDF, 688 KB

english, 1995

48

Nucleic Acid Interactions of Unfused Aromatic Cations: Evaluation of Proposed Minor-Groove, Major-Groove, and Intercalation Binding Modes

Wilson, W. David, Tanious, Farial A., Ding, Daoyuan, Kumar, Arvind, Boykin, David W., Colson, Pierre, Houssier, Claude, Bailly, Christian

Journal:

Journal of the American Chemical Society

Year:

1998

Language:

english

File:

PDF, 206 KB

english, 1998

49

Extended Aromatic Furan Amidino Derivatives as Anti- Pneumocystis carinii Agents

Hopkins, Katherine T., Wilson, W. David, Bender, Brendan C., McCurdy, Donald R., Hall, James Edwin, Tidwell, Richard R., Kumar, Arvind, Bajic, Miro, Boykin, David W.

Journal:

Journal of Medicinal Chemistry

Year:

1998

Language:

english

File:

PDF, 159 KB

english, 1998

50

Synthesis, DNA binding and antileishmanial activity of low molecular weight bis-arylimidamides

Banerjee, Moloy, Farahat, Abdelbasset A., Kumar, Arvind, Wenzler, Tanja, Brun, Reto, Munde, Manoj M., Wilson, W. David, Zhu, Xiaohua, Werbovetz, Karl A., Boykin, David W.

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 308 KB

english, 2012